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Movies News | Latest Movie Theaters Free Theaters | Movie Trailers Movie Clips Full Movie Download. Jurassic World: Fallen Kingdom India Movie Telugu Downlg Full Movie.-type=”table”}. The follow-up period ranged from 4 to 30 months. The median length of follow-up was 13 months. The initial complete remission (CR) rate in this study was 40.2%, and the median follow-up duration was 13 months. The 5-year OS rate was 62.5% and the 5-year DFS rate was 53.9% among the total cohort. The corresponding survival rates in this study were both higher than those of other studies.
Discussion
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Although the immune function of melanoma patients significantly improves, particularly after surgical resection of the primary tumor, the complete remission rate for patients with systemic metastasis has remained unchanged in the past decades. In our analysis, the initial CR rate for localized melanoma was 56.5%, which was close to that reported by Chung and colleagues (54.0%) and Okamoto and colleagues (57.5%) \[[@b2-medscimonit-22-14-b145],[@b12-medscimonit-22-14-b145]\], whereas the initial CR rate for regional metastasis in our study was 36.6%, similar to that reported by Rösel and colleagues (31.7%) \[[@b13-medscimonit-22-14-b145]\]. The metastatic sites of melanoma vary, and different treatments may be needed for various metastatic sites. In our study, the initial CR rate for both local and regional dissemination was higher for local metastasis than for regional metastasis, possibly due to the different responses of the immune system in different sites.
There were no survival differences among various metastatic sites in our multivariate analysis. However, after local resection, the time to relapse after resection was shorter in patients with regional dissemination than in those with local dissemination. This may be due to the different effects of chemotherapy or adjuvant immunotherapy on these 2 types of metastatic melanoma. Although our study demonstrated that the response to vaccination can be used to guide the administration of adjuvant vaccination for metastatic melanoma \[[@b14-medscimonit-22-14-b145]\], further study is needed to confirm our results.
There have been concerns that
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